Federal
- Bureau of Alcohol, Tobacco, Firearms and Explosives
- Bureau of Prisons – Metropolitan Detention Center (Guaynabo, PR)
- Customs and Border Protection
- Drug Enforcement Administration
- Federal Bureau of Investigation
- Homeland Security Investigations/Immigration and Customs Enforcement
- Internal Revenue Service
- Transportation Security Administration
- US Attorney’s Office for the District of Puerto Rico
- US Attorney’s Office for the District of the US Virgin Islands
- US Border Patrol – Ramey Sector
- US Coast Guard – Sector San Juan
- US Marshals Service for the District of Puerto Rico
- US Marshals Service for the District of US Virgin Islands
State and Local
- Alliance for a Drug Free Puerto Rico (ALIANZA)
- Puerto Rico Department of Health
- Puerto Rico Department of Corrections and Rehabilitation
- Puerto Rico Department of Justice
- Puerto Rico Department of Treasury
- Puerto Rico Forensic Bureau
- Puerto Rico National Guard
- Puerto Rico Police Bureau
- Puerto Rico Ports Authority
- San Juan Municipal Police Department
- Special Investigations Bureau (NIE)
- Virgin Islands Department of Justice – Attorney General’s Office
- Virgin Islands National Guard
- Virgin Islands Police Department
- Virgin Islands Department of Health